When it comes to weight loss, injections can be an option for some people, particularly those struggling with obesity or weight-related health conditions. These injections are designed to support weight loss efforts alongside diet, exercise and lifestyle changes. Understanding the options, effectiveness and safety is important before considering injectable treatments.

Common Injections Used for Weight Loss

One of the most widely prescribed injectable medications for weight loss is liraglutide (brand name Saxenda). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that helps regulate appetite and blood sugar levels. It works by slowing gastric emptying and increasing feelings of fullness, leading to reduced calorie intake.

Another newer option is semaglutide (brand name Wegovy), also a GLP-1 receptor agonist, which has shown even greater effectiveness in clinical trials for weight loss. Semaglutide can lead to significant reductions in body weight when combined with lifestyle changes.

How These Injections Work

Both liraglutide and semaglutide mimic the action of a natural hormone involved in appetite regulation. By targeting brain receptors, they reduce hunger and cravings, making it easier to stick to a calorie-controlled diet. They also improve insulin sensitivity and may provide benefits for blood sugar control.

Who Can Use Weight Loss Injections?

These injections are typically prescribed for adults with a body mass index (BMI) over 30, or over 27 with weight-related health conditions such as type 2 diabetes or high blood pressure. They are intended as part of a comprehensive weight management programme under medical supervision.

Potential Side Effects

Common side effects include nausea, vomiting, diarrhoea and constipation, which often improve over time. More serious side effects are rare but can include pancreatitis or gallbladder issues. It’s important to use these medications only under the guidance of a healthcare professional.

Alternatives and Considerations

Other injectable options include hormone-based therapies or treatments addressing specific medical causes of weight gain, but GLP-1 receptor agonists currently represent the most effective and widely used class for general weight loss.

Summary

The best injection for weight loss currently available and supported by strong evidence are GLP-1 receptor agonists like liraglutide and semaglutide. They help reduce appetite and support lifestyle changes for sustainable weight loss. Always consult a healthcare provider to determine the safest and most suitable option for your needs.

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