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Folate serum refers to the measurement of folate levels in the liquid part of the blood called serum or plasma. Folate, also known as vitamin B9, is a water-soluble vitamin essential for DNA synthesis, red blood cell formation and overall cellular function. Measuring serum folate helps assess a person’s current folate status.

Why Serum Folate Is Tested

A serum folate test is used to detect folate deficiency, which can lead to anaemia, fatigue, and in pregnant women, increased risk of birth defects. It can help diagnose nutritional deficiencies, malabsorption conditions, or monitor folate levels during supplementation.

Interpreting Serum Folate Levels

Serum folate reflects recent dietary intake and fluctuates more quickly than red blood cell folate, which indicates longer-term folate status. Normal serum folate levels typically range from about 3 to 17 ng/mL (7 to 39 nmol/L), though this may vary by laboratory.

Summary

Folate serum is the blood test measuring folate levels in the serum to evaluate recent folate intake and detect deficiencies. It plays a key role in diagnosing nutritional status and supporting health.