Training at Extreme Altitude: La Paz
La Paz, Bolivia sits at approximately 3500 metres above sea level with parts of the city reaching 4150 metres. It is the highest capital city in the world. Living and training at this altitude produces the most documented case of human population adaptation to chronic hypoxia outside specific genetically adapted groups. International football matches played in La Paz have produced significant performance differences for visiting teams. The case illustrates what extreme altitude living does to physiology and what visitors can expect when they travel to altitude.
What La Paz altitude means
La Paz is the de facto seat of government of Bolivia. The metropolitan area extends across a steep canyon with elevations ranging from approximately 3100 metres to over 4150 metres. The neighbouring city of El Alto sits at the higher elevations. The total population at altitudes above 3500 metres exceeds 1 million people.
The elevation
Central La Paz sits at approximately 3500 metres or 11500 feet above sea level. The Estadio Hernando Siles, where international football matches are played, sits at 3637 metres. El Alto and the upper portions of the city extend above 4000 metres. The elevations are well above the 2500 metre threshold at which significant altitude effects become measurable.
Atmospheric oxygen
At 3500 metres atmospheric pressure is approximately 490 mmHg compared to 760 mmHg at sea level. Oxygen partial pressure is approximately 100 mmHg compared to 160 mmHg at sea level. Each breath delivers approximately 65 percent of the oxygen molecules per breath that the same person would receive at sea level. This is sufficient for sustained life but significantly below sea level capacity.
The population
Bolivians born and raised at La Paz altitudes show specific physiological adaptations to chronic hypoxia. These adaptations differ in detail from those seen in Andean (Quechua and Aymara) genetic populations from longer altitude residence. The pattern is partly cultural and lifestyle, partly developmental and partly genetic. The combination produces functional adaptation that visitors cannot acquire quickly.
The international visitors
International football, rugby and other sports teams visiting La Paz have produced documented performance reductions. Bolivian football team has had unusually strong home record at altitude. FIFA briefly banned La Paz from international competition in 2007 to 2008 before reversing the decision. The altitude effect on visiting athletes is real and measurable.
What altitude living produces
Adaptation to chronic altitude differs from short term acclimatisation. The body changes over weeks and months in ways that brief altitude visits cannot produce. Long term La Paz residents show the population level pattern of these adaptations.
Increased haemoglobin
Chronic altitude exposure increases red blood cell production through elevated erythropoietin. Haemoglobin concentration in La Paz residents averages approximately 17 to 19 g/dL compared to 14 to 15 g/dL at sea level. The increased oxygen carrying capacity partly compensates for the reduced oxygen partial pressure. The adaptation takes 4 to 8 weeks to develop and weeks to fade after returning to sea level.
Increased capillary density
Tissues adapt to chronic hypoxia by increasing capillary density. The shorter diffusion distance between blood and cells improves oxygen delivery efficiency. This adaptation develops over months and represents one of the more durable altitude adaptations. Athletes who train at altitude for sustained periods retain some capillary density benefit when they return to sea level.
Lung adaptations
Children born and raised at altitude develop larger lung volumes than sea level matched populations. The effect is partly genetic and partly developmental. Lung adaptations are largely permanent in those who develop them in childhood and largely unavailable to adults who move to altitude. This is one reason native altitude athletes have advantages over adult migrants.
Cardiac adaptations
The right ventricle of the heart works harder at altitude due to increased pulmonary vascular resistance. Long term altitude residents show right ventricular adaptation that is helpful at altitude but produces specific cardiac considerations at sea level. Some adaptations may not be entirely beneficial outside the altitude environment.
What altitude does to non adapted visitors
Athletes visiting La Paz without specific altitude preparation face significant performance challenges. The reduced oxygen partial pressure affects endurance performance more than strength or skill performance.
Acute altitude sickness
Some visitors develop acute mountain sickness with symptoms including headache, nausea, fatigue and sleep disturbance. Symptoms typically appear within hours to days and may take a week or more to resolve. Severe cases can develop high altitude pulmonary or cerebral oedema. Most visitors to La Paz develop at least mild symptoms in the first days.
Performance reduction
Endurance performance at La Paz altitude is reduced by 10 to 15 percent compared to sea level performance for non acclimatised visitors. The reduction is largest in events lasting 4 to 60 minutes where aerobic energy systems dominate. Sprint and pure power events are affected less. Skill based sports like football see specific effects on running capacity at high effort levels.
Acclimatisation timeline
Short visits of 1 to 7 days produce minimal acclimatisation. 2 to 4 weeks of altitude residence produces measurable adaptation. 6 to 8 weeks produces substantial adaptation but never quite matches lifelong altitude residence. International sport schedules rarely allow enough time for full adaptation. Most visiting teams arrive 1 to 3 days before competition.
The home altitude advantage
Bolivian sports teams playing at home in La Paz benefit from the visiting team adaptation deficit. The home advantage at altitude is larger than typical home advantages at sea level. This is the primary reason FIFA briefly banned La Paz from international competition. The ban was reversed but the home advantage at extreme altitude remains documented.
Lessons from La Paz altitude
The La Paz case demonstrates what chronic altitude exposure does to physiology and what short term visits cannot produce. The lessons inform athletic preparation for altitude competition and broader understanding of altitude adaptation.
Adaptation takes time
Short altitude visits produce minimal acclimatisation. Athletes competing at altitude either need to arrive multiple weeks before competition or accept performance reduction. The standard protocols of arriving 1 to 3 days before competition are largely inadequate. The choice often comes down to logistical compromise rather than ideal preparation.
Native altitude advantage is real
Athletes born and raised at altitude have advantages over adult migrants that are difficult to replicate. The advantages include developmental lung capacity changes, capillary density and chronic adaptations to elevated haemoglobin. Adult altitude training produces some but not all of these benefits. The Kenyan and Ethiopian distance running dominance reflects altitude living combined with other cultural and genetic factors.
Live high train low works
Research has shown that living at moderate altitude (2000 to 2500 metres) while training at lower altitudes produces performance benefits at sea level. The pattern allows altitude adaptations to develop without the training quality reductions that occur at high altitude. Many elite endurance athletes now use this protocol. La Paz altitude is too high for productive training but acceptable for living.
Altitude is not always beneficial
Athletes who move to high altitude for training sometimes underperform compared to sea level training. Training intensity drops at altitude. Quality of high intensity work suffers. The benefits of altitude adaptation can be offset by training quality reduction. Modern altitude training is more sophisticated than simply moving athletes to altitude and waiting for adaptation.
The La Paz case sits in the limits archive among altitude adaptation and environmental physiology cases. For other altitude and extreme environment cases, see our Breaking Human Limits hub.
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More from the limits library
For another altitude case, our Climbing Everest Without Oxygen guide covers Reinhold Messner. Fourteen Eight Thousand Metre Peaks covers Nimsdai Purja. And Running on Minimal Body Fat covers Haile Gebrselassie and Ethiopian highland running tradition.


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